RNA REGULATION IN HEALTH AND DISEASE

We study multiple aspects of RNA and are interested in how its dysregulation plays a role in repeat expansion diseases. These diseases are caused by repetitive DNA sequences that can be transcribed into toxic RNA and toxic proteins. We are particularly focused on Myotonic Dystrophy (DM), a multi-systemic disease that affects skeletal muscle, heart, and the central nervous system. We seek to make fundamental insights into how cells function, and hope to harness these insights to develop treatments for patients living with neuromuscular and neurological disease.

News

  • December 2018

    The Chan-Zuckerberg Initiative awards the lab a 5-year, $2.5M Ben Barres Career Acceleration Award to study neurodegeneration!

  • August 2018

    Muscular Dystrophy Association awards the lab a Research Grant to study CNS issues in DM!

  • October 2017

    Our paper on using dCas9 to impede transcription of repeat expansions is published in Molecular Cell. A companion Preview was also published to discuss this work.

  • Spring 2015

    In Fall 2015, the lab will be moving to the University of Florida! We will be in the Department of Molecular Genetics and Microbiology, and the Center for Neurogenetics. Watch our story below (we made this video for Promise To Kate).

  • March 7, 2015

    We were honored to once again to be guests at the Promise to Kate benefit in Jacksonville, Florida.

  • November 7, 2014

    Eric co-hosts the 2nd Strength, Science & Stories of Inspiration benefit at the MIT Museum. Click here to see the Facebook page for this annual event.

  • August 19, 2014

    Francis Collins, Director of the NIH, features our NIH Common Fund video on his blog!

  • May 6, 2014

    Lab member Ona McConnell is featured in Ivy League Athletes, a book about "nine student-athletes from seven Ivy League campuses through the 2011–2012 season", and the "qualities of heart, mind, and body that got them there and allow them to prosper on the field and in the classroom.

  • May 9, 2014

    Our video was selected as a winner in the NIH Common Fund Video Contest! It will featured at the NIH Common Fund 10 Year Commemoration Symposium in June.

  • March 1, 2014

    Eric is guest speaker at the Promise To Kate gala dinner event in Jacksonville, Florida. Promise To Kate was founded to "honor Kate Conte and help fund research for myotonic dystrophy".

  • October 16, 2013

    Eric co-chairs the keynote session at the 9th International Myotonic Dystrophy Consortium Meeting.

  • September 30, 2013

    Eric receives the NIH Early Independence Award. Given through the NIH Common Fund as part of its "High-Risk, High-Reward Program", this award provides a mechanism for exceptional early career scientists to move rapidly into independent research positions by essentially omitting the traditional post-doctoral training period.

  • September 16, 2013

    Eric co-hosts Strength, Science & Stories of Inspiration, a benefit event in Boston aimed at bringing together all stakeholders for muscle diseases. Click here to see the Facebook page for this annual event.

Contact

  • Email:

    eric dot t dot wang at ufl dot edu

  • Fedex Packages/Lab:

    Eric Wang Lab
    Center for Neurogenetics, University of Florida
    2033 Mowry Road, Room 215
    Gainesville, FL 32610

  • USPS Mail/Office:

    Eric Wang Lab
    Center for Neurogenetics, University of Florida
    2033 Mowry Road, Room 204
    Gainesville, FL 32610

    (352) 273-7601